A Pioneer in Regenerative Aesthetics
Advancing the Science of CaHA
Aphranel is a CaHA regenerative filler innovated in China, developed at the intersection of material science and regenerative aesthetics. Inspired by structural design and the passage of time, it supports facial architecture while promoting natural regeneration—delivering results that evolve rather than transform abruptly, with immediate structural support, collagen stimulation, and fully degradable with no residual material over time.
At the heart of the brand lies its philosophy, "The Poetics of Time"—instead of fighting against time, Aphranel chooses to work in harmony with time: supporting structure, respecting change, and allowing beauty to unfold naturally. Because true beauty is not created in a moment. It is built over time.
Aphranel is a CaHA regenerative filler innovated in China, developed at the intersection of material science and regenerative aesthetics. Inspired by structural design and the passage of time, it supports facial architecture while promoting natural regeneration—delivering results that evolve rather than transform abruptly, with immediate structural support, collagen stimulation, and fully degradable with no residual material over time.
At the heart of the brand lies its philosophy, "The Poetics of Time"—instead of fighting against time, Aphranel chooses to work in harmony with time: supporting structure, respecting change, and allowing beauty to unfold naturally. Because true beauty is not created in a moment. It is built over time.
One CaHA System, Multiple Aesthetic Possibilities
An evolving portfolio of advanced CaHA formulations, designed to support structure and regeneration, delivering predictable, long-term aesthetic outcomes.
Where Innovation Meets Scientific Integrity
Rooted in independent research and a pursuit of excellence, we push the boundaries of regenerative medicine, setting new benchmarks in safety and performance.
High G′ Value
Up to 10× higher than conventional HA fillers, delivering superior structural support and projection.
Ultra-high porosity
The number of raspberry-shaped porous microspheres is 6.1 times that of another CaHA filler, featuring up to 74% porosity, delivering superior regeneration effects.
Biodegradation
Fully degradable according to official standards, ensuring safety and long-term compatibility.
CaHA Microspheres
More than 35 million CaHA microspheres per mL,each composed of approximately 160 million nanoscale subunits.
At Aphranel, we believe beauty is not about becoming someone else, but about becoming your true self.
Guided by our philosophy of "Be with time, be like me," we embrace a more natural, progressive approach—working with time, not against it.
Through regenerative science, we support beauty that evolves, strengthens, and belongs to each individual.
