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MagiCCrystal Novo®: CaHA Regenerative Filler by Aphranel®

aphranel® MagiCCrystal Novo

Precision Structural Support. Regeneration Over Time.

Modern aesthetic medicine is no longer defined by immediate transformation alone. Increasingly, both patients and physicians are seeking regenerative solutions that respect individuality, support natural aging, and deliver results that evolve gracefully over time.


aphranel® MagiCCrystal Novo is a regenerative CaHA (Calcium Hydroxyapatite)-based injectable filler designed for structural support, contour enhancement, and collagen regeneration. Developed with a dual-regeneration mechanism and a structural system composed of 30% CaHA microspheres and 70% CMC gel carrier, it provides immediate structural support while supporting progressive collagen regeneration.


As structure and regeneration work together over time, aphranel® helps create aesthetic outcomes that are balanced, natural-looking, and enduring.

Aphranel® MagiCCrystal Novo CaHA filler — three dimensions of regenerative aesthetics: immediate shaping, evolving regeneration, controlled degradation

Composition

Dual-Regeneration Structural System: Developed with a dual-regeneration mechanism and a structural system composed of 30% CaHA microspheres and 70% CMC gel carrier, aphranel® MagiCCrystal Novo provides immediate structural support while supporting progressive collagen regeneration.


Over time, structural refinement and natural collagen regeneration work in harmony, delivering aesthetic outcomes that are balanced, natural-looking, and long-lasting.


30% CaHA Microspheres:Designed to provide structural support and biostimulatory activity, the CaHA microspheres are engineered with a controlled particle size distribution of approximately 30–35 μm, supporting tissue integration and collagen regeneration.


70% CMC Gel Carrier:Acts as a carrier matrix to ensure smooth injectability, uniform microsphere distribution, and stable product placement, while supporting controlled biodegradation over time.

Aphranel® MagiCCrystal Novo dual-regeneration system: 30% CaHA microspheres and 70% CMC gel carrier

Core Technologies

ACD-MT® PATENTED MICROSPHERE TECHNOLOGY:

Accurate Controllable Degradation

Microsphere Technology

ACD-MT® microsphere technology of Aphranel®: 30–35μm uniform particle size, large specific surface area, raspberry-shaped porous surface, through-hole structure

PCD-ETT® PATENTED CMC GEL TECHNOLOGY:

Physical Crosslinking Dynamic

Entanglement Topology Technology

PCD-ETT® CMC gel technology of Aphranel® — no cross-linking agents, gradual biodegradation without residue
PCD-ETT® CMC gel technology of Aphranel® — uniformly distributed CaHA microspheres for smooth injection
PCD-ETT® CMC gel technology of Aphranel® — high G' viscoelasticity of 5500 Pa for strong structural support
PCD-ETT® CMC gel technology of Aphranel® — osmotic pressure of approximately 299 mOsm/kg close to human physiological conditions
HOW IT WORKS

Mechanism of Action

Aphranel® MagiCCrystal Novo 7-step mechanism of action: injection, immediate support, carrier resorption, collagen regeneration, controlled biodegradation, long-term natural results

Global Certifications

Aphranel® MagiCCrystal Novo global certifications: China NMPA Class III, EU MDR and Saudi SFDA

Case Interaction

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